Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198227 | 0.84 | MAPK1 (0.56) | MAPK1HSD17B10MEN1KMT2ANPC1 | |
| SCHEMBL9198069 | 0.80 | KMT2A (0.42) | GAAHTTLMNAMAPK1HSD17B10 | |
| SCHEMBL9204514 | 0.75 | TDP1 (0.51) | GAAHTTLMNAHSD17B10BCL2 | |
| SCHEMBL9198091 | 0.75 | HTT (0.66) | GAAHTTLMNABCL2MAPT | |
| SCHEMBL9203707 | 0.75 | DHODH (0.56) | GAAHTTLMNABCL2HPGD | |
| SCHEMBL9201772 | 0.74 | GAA (0.37) | GAAHTTLMNAMAPK1HSD17B10 | |
| SCHEMBL9199865 | 0.74 | PKM (0.53) | LMNAMAPTHPGDL3MBTL1MEN1 | |
| SCHEMBL9204272 | 0.74 | AKR1C3 (0.57) | GAALMNAMAPK1MAPTKDM4E | |
| SCHEMBL9200578 | 0.74 | HPGD (0.49) | GAAHTTLMNAMAPK1MAPT | |
| SCHEMBL9205680 | 0.73 | SMN1; SMN2 (0.53) | HTTLMNAMAPK1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | claimed |