Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203707 | 0.80 | DHODH (0.56) | RAB9ANPC1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL27310635 | 0.79 | PKM (0.63) | PKMANO1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9198091 | 0.78 | HTT (0.66) | PKMRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL9204333 | 0.77 | GRM1 (0.53) | PKMRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL9204272 | 0.76 | AKR1C3 (0.57) | PKMRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL9205680 | 0.75 | SMN1; SMN2 (0.53) | PKMRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL9202966 | 0.74 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL9197115 | 0.74 | GAA (0.37) | RAB9ANPC1MAPTHPGDMEN1 | |
| SCHEMBL17660207 | 0.74 | PKM (0.67) | PKMRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL9199984 | 0.74 | TDP1 (0.54) | MAPTMEN1KMT2ALMNAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | claimed |