SCHEMBL9197192

SCHEMBL9197192

NS(=O)(=O)c1ccccc1SCC(F)Cl

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 17/20 0.39
CA1 P00915 15/20 0.39
CA9 Q16790 13/20 0.39
CA12 O43570 10/20 0.39
CA14 Q9ULX7 8/20 0.39
CA7 P43166 7/20 0.39
CA4 P22748 6/20 0.39
CA6 P23280 6/20 0.39
CA5B Q9Y2D0 5/20 0.39
CA5A P35218 3/20 0.39
CYP2C9 P11712 1/20 0.39
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
CA13 Q8N1Q1 4/20 0.34
CA3 P07451 3/20 0.34
PTGES2 Q9H7Z7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9202368 0.87 CA2 (0.41) CA2CA1CA9CA12CA14
SCHEMBL14322784 0.80 CA2 (0.45) CA2CA1CA9CA12CA14
SCHEMBL9345418 0.75 CA2 (0.42) CA2CA1CA9CA12CA14
SCHEMBL7545831 0.74 ALOX15 (0.46) CA2CA1CA9CA12CA14
SCHEMBL11172963 0.74 CA2 (0.45) CA2CA1CA9CA12CA14
SCHEMBL14322682 0.73 CA2 (0.42) CA2CA1CA9CA12CA14
SCHEMBL6073395 0.72 CA1 (0.36) CA2CA1CA9CA12CA14
SCHEMBL10567696 0.71 CA1 (0.50) CA2CA1CA9CA12CA14
SCHEMBL1185311 0.71 CA2 (0.68) CA2CA1CA9CA12CA14
SCHEMBL9269411 0.70 CA2 (0.54) CA2CA1CA9CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0471646-B1 Sulfonylureas as herbicides CIBA GEIGY AG (CH) 1995-09-13 EP disclosed
US-5306693-A Herbicides, plant growth regulators CIBA-GEIGY CORPORATION (US) 1994-04-26 US disclosed
EP-0420815-B1 Process for the preparation of 2-(2-haloethylthio)-phenylsulfonamides CIBA GEIGY AG (CH) 1994-01-19 EP disclosed
US-5166430-A PROCESS FOR THE PREPARATION OF 2-(2-HALOGENOETHYLTHIO)-PHENYLSULFONAMIDES CIBA-GEIGY CORPORATION (US) 1992-11-24 US disclosed
US-5163996-A Herbicides CIBA-GEIGY CORPORATION (US) 1992-11-17 US disclosed
EP-0471646-A2 Sulfonylureas as herbicides CIBA-GEIGY AG (CH) 1992-02-19 EP disclosed
EP-0420815-A1 Process for the preparation of 2-(2-haloethylthio)-phenylsulfonamides CIBA-GEIGY AG (CH) 1991-04-03 EP disclosed