Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.36 |
| ▸ | CA2 | P00918 | 11/20 | 0.36 |
| ▸ | CA9 | Q16790 | 10/20 | 0.36 |
| ▸ | CA4 | P22748 | 7/20 | 0.36 |
| ▸ | CA7 | P43166 | 7/20 | 0.36 |
| ▸ | CA12 | O43570 | 7/20 | 0.36 |
| ▸ | CA6 | P23280 | 7/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.36 |
| ▸ | CA5A | P35218 | 6/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202368 | 0.74 | CA2 (0.41) | CA1CA2CA9CA4CA7 | |
| SCHEMBL14322784 | 0.74 | CA2 (0.45) | CA1CA2CA9CA4CA7 | |
| SCHEMBL9197192 | 0.72 | CA2 (0.39) | CA1CA2CA9CA4CA7 | |
| SCHEMBL2944706 | 0.71 | MAOA (0.50) | MAOAMAOBALDH1A1 | |
| SCHEMBL7545831 | 0.69 | ALOX15 (0.46) | CA1CA2CA9CA4CA7 | |
| SCHEMBL10567696 | 0.66 | CA1 (0.50) | CA1CA2CA9CA4CA7 | |
| SCHEMBL9345418 | 0.66 | CA2 (0.42) | CA1CA2CA9CA4CA7 | |
| SCHEMBL1185311 | 0.66 | CA2 (0.68) | CA1CA2CA9CA4CA7 | |
| SCHEMBL9269411 | 0.66 | CA2 (0.54) | CA1CA2CA9CA4CA7 | |
| SCHEMBL11127274 | 0.65 | CA2 (0.41) | CA1CA2CA9CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006011035-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS; PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LTD. (US) | 2006-02-02 | — | — | WO | claimed |