Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 13/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9476259 | 0.89 | PTGES (0.58) | PTGESALOX5FFAR1APP | |
| SCHEMBL9192563 | 0.86 | PTGES (0.56) | PTGESALOX5PTGS1PTGS2 | |
| SCHEMBL9197210 | 0.84 | PTGES (0.58) | PTGESALOX5PTGS1PTGS2FFAR1 | |
| SCHEMBL9196097 | 0.84 | PTGES (0.56) | PTGESFFAR1ACACBAPP | |
| SCHEMBL9195229 | 0.83 | ACACB (0.48) | PTGESALOX5PTGS1PTGS2ACACB | |
| SCHEMBL9193618 | 0.82 | PTGES (0.62) | PTGESALOX5PTGS1PTGS2FFAR1 | |
| SCHEMBL9197154 | 0.82 | PTGES (0.50) | PTGESACACB | |
| SCHEMBL9197649 | 0.77 | PTGES (0.59) | PTGESALOX5PTGS1PTGS2FFAR1 | |
| SCHEMBL9191848 | 0.76 | PTGES (0.50) | PTGESALOX5FFAR1ACACB | |
| SCHEMBL9192515 | 0.75 | HRH3 (0.48) | PTGESALOX5PTGS1PTGS2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4243856-A | — | — | None | — | — | JP | disclosed |
| EP-0468281-B1 | Substituted phenylacetylenes, pharmaceuticals containing them and methods for the preparation of these compounds and pharmaceuticals | GRUENENTHAL GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5202349-A | Lipoxygenase inhibitors, antiasthatics | GRUENENTHAL GMBH (DE) | 1993-04-13 | — | — | US | disclosed |
| JP-H04243856-A | SUBSTITUTED PHENYLACETYLENE, MEDICINE CONTAINING THE SAME AND PRODUCTION OF THE COMPOUND AND THE MEDICINE | GRUENENTHAL GMBH | 1992-08-31 | — | — | JP | disclosed |
| EP-0468281-A1 | Substituted phenylacetylenes, pharmaceuticals containing them and methods for the preparation of these compounds and pharmaceuticals | Grünenthal GmbH (DE) | 1992-01-29 | — | — | EP | disclosed |