SCHEMBL9197880

SCHEMBL9197880

CN(C)Cc1cc(-c2cccs2)sc1-c1cccs1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.37
HTR1D P28221 1/20 0.36
HTR1B P28222 1/20 0.36
DPP4 P27487 3/20 0.36
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 1/20 0.36
PRMT6 Q96LA8 1/20 0.36
MAPT P10636 2/20 0.35
LMNA P02545 1/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP17A1 P05093 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20146971 0.81 KDM4E (0.42) LTA4HDPP4KDM4EALDH1A1NPC1
SCHEMBL22343408 0.78 DPP4 (0.50) LTA4HDPP4KDM4EALDH1A1NPC1
SCHEMBL365923 0.77 DPP4 (0.45) LTA4HDPP4KDM4EALDH1A1NPC1
SCHEMBL10070116 0.75 DPP4 (0.44) LTA4HDPP4KDM4EALDH1A1NPC1
SCHEMBL14590760 0.75 SREBF2 (0.37) LTA4HDPP4KDM4EALDH1A1NPC1
SCHEMBL10062482 0.74 DPP4 (0.48) LTA4HDPP4KDM4EALDH1A1NPC1
SCHEMBL2608116 0.74 ADK (0.39) LTA4HDPP4KDM4EALDH1A1NPC1
SCHEMBL12424299 0.73 DPP4 (0.49) LTA4HDPP4KDM4EALDH1A1NPC1
SCHEMBL352568 0.73 ALDH1A1 (0.47) DPP4KDM4EALDH1A1NPC1RAB9A
SCHEMBL16160826 0.73 ALDH1A1 (0.45) LTA4HDPP4KDM4EALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0454204-B1 Method for the photochemical isomeration of organic compounds under the influence of a photosensitizer DUPHAR INT RES (NL) 1995-06-28 EP disclosed
US-5252191-A Method for the photochemical isomerization of organic compounds under the influence of a photosensitizer DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1993-10-12 US disclosed
EP-0454204-A2 Method for the photochemical isomeration of organic compounds under the influence of a photosensitizer DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1991-10-30 EP disclosed