Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196698 | 0.98 | MEN1 (0.40) | HPGDCYP3A4CYP2D6CYP2C9PKM | |
| SCHEMBL9199733 | 0.89 | ELANE (0.33) | HPGDCYP3A4CYP2D6CYP2C9PKM | |
| SCHEMBL9197301 | 0.87 | ELANE (0.34) | CYP2C9MEN1KMT2A | |
| SCHEMBL9198707 | 0.86 | CEL (0.41) | LMNAMEN1KMT2ARAB9A | |
| SCHEMBL9196131 | 0.85 | MEN1 (0.34) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9198549 | 0.85 | MEN1 (0.34) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6173304 | 0.84 | HTR2B (0.43) | NPC1RAB9A | |
| SCHEMBL9198902 | 0.83 | PPARG (0.32) | — | |
| SCHEMBL6175129 | 0.83 | ELANE (0.33) | CYP2C9MEN1KMT2A | |
| SCHEMBL9201135 | 0.83 | ELANE (0.47) | HPGDMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-30 | — | — | EP | claimed |