Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4310302 | 0.80 | HTR2A (0.33) | SLC6A2SLC6A4SLC6A3PRCPHTR2A | |
| SCHEMBL1009380 | 0.77 | HTR2A (0.38) | HTR2AIDO1 | |
| SCHEMBL9199555 | 0.76 | MAPT (0.32) | PDPK1HTR2AIDO1 | |
| SCHEMBL4310550 | 0.76 | MAPT (0.32) | PDPK1HTR2AIDO1 | |
| SCHEMBL8492145 | 0.72 | PDPK1 (0.32) | PDPK1 | |
| SCHEMBL455641 | 0.69 | HTR2A (0.34) | PRCPHTR2A | |
| SCHEMBL3389204 | 0.67 | HTR2A (0.35) | PDPK1HTR2AGRIN1GRIN2BIDO1 | |
| SCHEMBL8890669 | 0.67 | CHRNB2 (0.33) | PDPK1HTR2AOPRM1GRIN1GRIN2B | |
| SCHEMBL3634708 | 0.67 | PRCP (0.38) | SLC6A2SLC6A4SLC6A3PRCPHTR2A | |
| SCHEMBL458495 | 0.66 | HTR2A (0.35) | PDPK1PRCPHTR2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | claimed |