Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 9/20 | 0.38 |
| ▸ | HRH1 | P35367 | 3/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 5/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4310302 | 0.80 | HTR2A (0.33) | HTR2AHRH1RETHTR2C | |
| SCHEMBL9198328 | 0.77 | CTSL (0.40) | HTR2AIDO1 | |
| SCHEMBL9199555 | 0.76 | MAPT (0.32) | HTR2AHRH1IDO1 | |
| SCHEMBL4310550 | 0.76 | MAPT (0.32) | HTR2AHRH1IDO1 | |
| SCHEMBL8492145 | 0.72 | PDPK1 (0.32) | — | |
| SCHEMBL12228575 | 0.69 | IDO1 (0.42) | HTR2AHRH1RETHTR2CIDO1 | |
| SCHEMBL3389204 | 0.67 | HTR2A (0.35) | HTR2AHRH1RETHTR2CIDO1 | |
| SCHEMBL8890669 | 0.67 | CHRNB2 (0.33) | HTR2A | |
| SCHEMBL7410008 | 0.67 | IDO1 (0.61) | HTR2AHRH1RETIDO1 | |
| SCHEMBL458123 | 0.66 | HTR2A (0.34) | HTR2AHRH1RETHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268273-A1 | SMALL-MOLECULE MODULATORS OF TRP-P8 ACTIVITY | DENDREON CORPORATION (US) | 2011-01-05 | — | — | EP | claimed |
| WO-2009067410-A1 | SMALL-MOLECULE MODULATORS OF TRP-P8 ACTIVITY | DENDREON CORPORATION (US) | 2009-05-28 | — | — | WO | claimed |