Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195354 | 0.81 | L3MBTL1 (0.64) | L3MBTL1KLKB1MAPTPHGDHPPARG | |
| SCHEMBL21580166 | 0.80 | L3MBTL1 (0.51) | L3MBTL1KLKB1MAPTPHGDHTP53 | |
| SCHEMBL9587518 | 0.80 | L3MBTL1 (0.53) | L3MBTL1EPHX2NR1H4KLKB1MAPT | |
| SCHEMBL9587530 | 0.78 | L3MBTL1 (0.54) | L3MBTL1KLKB1MAPTPHGDHPPARG | |
| SCHEMBL21702522 | 0.72 | L3MBTL1 (0.52) | L3MBTL1MAPTPHGDHPPARGPPARD | |
| SCHEMBL12804334 | 0.71 | ALDH1A1 (0.60) | L3MBTL1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31043936 | 0.71 | MAPT (0.49) | L3MBTL1MAPTTP53SMN1; SMN2LMNA | |
| SCHEMBL13967467 | 0.71 | EPHX2 (0.76) | L3MBTL1EPHX2NR1H4SMN1; SMN2LMNA | |
| SCHEMBL12501227 | 0.71 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL7699111 | 0.70 | NPC1 (0.63) | L3MBTL1MAPTTP53ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365925-B1 | Pyrazole amides and insecticide and miticide containing them as active ingredient | MITSUBISHI CHEM CORP (JP) | 1995-07-19 | — | — | EP | disclosed |
| EP-0289879-B1 | PYRAZOLE DERIVATIVE, INSECTICIDAL OR MITICIDAL COMPOSITION CONTAINING THE SAME AS THE EFFECTIVE INGREDIENT | MITSUBISHI KASEI CORPORATION (JP) | 1993-03-17 | — | — | EP | disclosed |
| EP-0307801-B1 | PYRAZOLE DERIVATIVE AND INSECTICIDAL AND MITICIDAL COMPOSITION CONTAINING THE DERIVATIVE AS ACTIVE INGREDIENT | MITSUBISHI KASEI CORPORATION (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-5039693-A | Pyrazole amides and insecticide and miticide containing them as active ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1991-08-13 | — | — | US | disclosed |
| US-4968805-A | Pyrazole derivatives and insecticidal fungicidal and miticidal compositions thereof | MITSUBISHI KASEI CORPORATION (JP) | 1990-11-06 | — | — | US | disclosed |
| US-4950668-A | Pyrazole derivative, insecticidal or miticidal composition containing the same as the effective ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1990-08-21 | — | — | US | disclosed |
| EP-0365925-A1 | Pyrazole amides and insecticide and miticide containing them as active ingredient | Mitsubishi Chemical Corporation (JP) | 1990-05-02 | — | — | EP | disclosed |
| US-4861777-A | Pyrazole derivative and insecticidal and miticidal composition containing the derivative as active ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1989-08-29 | — | — | US | disclosed |
| EP-0329020-A1 | Pyrazole derivatives, processes for their manufacture and insecticidal, miticidal and fungicidal compositions containg the derivatives as active ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0307801-A1 | Pyrazole derivative and insecticidal and miticidal composition containing the derivative as active ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1989-03-22 | — | — | EP | disclosed |
| EP-0289879-A1 | Pyrazole derivative, insecticidal or miticidal composition containing the same as the effective ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1988-11-09 | — | — | EP | disclosed |