Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200672 | 0.88 | CYP4F2 (0.39) | ACHEALDH1A1PDK1PDK2PDK4 | |
| SCHEMBL9203046 | 0.87 | CYP4F2 (0.38) | PPARGPPARAALDH1A1PDK1PDK2 | |
| SCHEMBL9206935 | 0.86 | SLC7A5 (0.35) | NR1H4SLC7A5ALDH1A1PDK2HPGD | |
| SCHEMBL9206588 | 0.86 | CYP11B1 (0.34) | ALOX5ALDH1A1PDK1PDK2PDK4 | |
| SCHEMBL9203593 | 0.85 | CYP2D6 (0.34) | ALOX5HDAC1ALDH1A1PDK1PDK2 | |
| SCHEMBL9202975 | 0.84 | CYP2D6 (0.39) | ALOX5PPARGPPARAALDH1A1HPGD | |
| SCHEMBL9199128 | 0.83 | HSD17B2 (0.40) | ALDH1A1HPGDSMN1; SMN2CYP2D6MAPT | |
| SCHEMBL9198805 | 0.82 | EPHX2 (0.38) | NR1H4HDAC3ACHEALDH1A1HPGD | |
| SCHEMBL9202154 | 0.81 | ALDH1A1 (0.41) | ALDH1A1PDK2HPGDSMN1; SMN2CYP2D6 | |
| SCHEMBL9208251 | 0.74 | PRSS1 (0.33) | ALDH1A1HPGDSMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |