Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199128 | 0.86 | HSD17B2 (0.40) | ALDH1A1HPGDSMN1; SMN2MAPTLMNA | |
| SCHEMBL9198805 | 0.85 | EPHX2 (0.38) | ALDH1A1HPGDSMN1; SMN2KIF11KMT2A | |
| SCHEMBL9207327 | 0.84 | ALDH1A1 (0.45) | ALDH1A1HPGDSMN1; SMN2KMT2AMAPT | |
| SCHEMBL9198641 | 0.81 | NR1H4 (0.36) | ALDH1A1HPGDSMN1; SMN2KMT2AMAPT | |
| SCHEMBL9203895 | 0.81 | MEN1 (0.51) | ALDH1A1HPGDSMN1; SMN2KIF11KMT2A | |
| SCHEMBL9204169 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HPGDSMN1; SMN2KIF11KMT2A | |
| SCHEMBL9206935 | 0.80 | SLC7A5 (0.35) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9204754 | 0.78 | LMNA (0.44) | ALDH1A1HPGDSMN1; SMN2KIF11KMT2A | |
| SCHEMBL7615069 | 0.77 | AKR1C3 (0.50) | ALDH1A1KMT2AMEN1TP53CYP3A4 | |
| SCHEMBL9203802 | 0.76 | BCHE (0.41) | ALDH1A1HPGDSMN1; SMN2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |