Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200540 | 0.86 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL9200976 | 0.83 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL9194304 | 0.82 | LMNA (0.57) | KDM4EALDH1A1HPGDRPS6KB1KMT2A | |
| SCHEMBL9199361 | 0.82 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL9198579 | 0.81 | KMT2A (0.59) | KDM4EALDH1A1HPGDSLC40A1KMT2A | |
| SCHEMBL9200741 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1HPGDSLC40A1KMT2A | |
| SCHEMBL9200697 | 0.75 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL9200974 | 0.75 | KMT2A (0.47) | KDM4EALDH1A1HPGDSLC40A1KMT2A | |
| SCHEMBL9194491 | 0.75 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL9344910 | 0.74 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471841-B1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ASAHI CHEMICAL IND (JP) | 1995-11-02 | — | — | EP | disclosed |
| US-5340811-A | Bronchodilator agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0471841-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-02-26 | — | — | EP | disclosed |