Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.45 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.45 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.45 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | COMT | P21964 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9345579 | 0.84 | TSHR (0.51) | KDM4EALDH1A1HPGDHSD17B10FTO | |
| SCHEMBL9198904 | 0.82 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10FTO | |
| SCHEMBL14919776 | 0.81 | ALDH1A1 (0.78) | KDM4EALDH1A1HPGDHSD17B10FTO | |
| SCHEMBL2371992 | 0.80 | FTO (0.50) | KDM4EALDH1A1HPGDHSD17B10FTO | |
| SCHEMBL9198579 | 0.80 | KMT2A (0.59) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL9397232 | 0.79 | TSHR (0.53) | KDM4EALDH1A1HPGDHSD17B10FTO | |
| SCHEMBL9344872 | 0.79 | TSHR (0.53) | KDM4EALDH1A1HPGDHSD17B10FTO | |
| SCHEMBL9198656 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL9198856 | 0.78 | COMT (0.69) | KDM4EALDH1A1HPGDHSD17B10FTO | |
| SCHEMBL16831996 | 0.77 | KMT2A (0.48) | KDM4EALDH1A1HSD17B10KMT2ACSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471841-B1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ASAHI CHEMICAL IND (JP) | 1995-11-02 | — | — | EP | disclosed |
| US-5340811-A | Bronchodilator agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0471841-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-02-26 | — | — | EP | disclosed |