Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199787 | 0.90 | LMNA (0.56) | MAPTLMNAL3MBTL1RAB9AATM | |
| SCHEMBL9195985 | 0.89 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1HTTHPGDNPSR1 | |
| SCHEMBL9199006 | 0.83 | ALDH1A1 (0.51) | ALDH1A1HTTTDP1RXRA | |
| SCHEMBL1097551 | 0.82 | SGMS2 (0.54) | MAPTLMNAL3MBTL1RAB9AALDH1A1 | |
| SCHEMBL9195901 | 0.82 | LMNA (0.55) | MAPTLMNAL3MBTL1RAB9AATM | |
| SCHEMBL8304467 | 0.81 | ALDH1A1 (0.51) | RAB9AALDH1A1HTTHPGDNPSR1 | |
| SCHEMBL24832772 | 0.80 | ALDH1A1 (0.63) | MAPTLMNAL3MBTL1RAB9AALDH1A1 | |
| SCHEMBL9203364 | 0.79 | HTT (0.47) | L3MBTL1RAB9AALDH1A1HTTHPGD | |
| SCHEMBL22388846 | 0.79 | KMT2A (0.76) | MAPTLMNARAB9AALDH1A1HPGD | |
| SCHEMBL28376684 | 0.78 | MAPT (0.63) | MAPTLMNAL3MBTL1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | disclosed |