Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199012 | 0.90 | MAPT (0.54) | LMNARAB9AMAPTL3MBTL1ATM | |
| SCHEMBL28376684 | 0.85 | MAPT (0.63) | LMNARAB9AMAPTL3MBTL1ATM | |
| SCHEMBL9195901 | 0.84 | LMNA (0.55) | LMNARAB9AMAPTL3MBTL1ATM | |
| SCHEMBL9199781 | 0.82 | PTGER1 (0.55) | MAPTL3MBTL1ATMPTGER1RXRA | |
| SCHEMBL1097551 | 0.81 | SGMS2 (0.54) | LMNARAB9AMAPTL3MBTL1PTGER1 | |
| SCHEMBL9195985 | 0.81 | ALDH1A1 (0.55) | L3MBTL1PTGER1RXRAHPGDALDH1A1 | |
| SCHEMBL1097870 | 0.81 | FOLH1 (0.62) | MAPTL3MBTL1PTGER1NPC1ALDH1A1 | |
| SCHEMBL8325228 | 0.80 | RAB9A (0.56) | LMNARAB9AMAPTL3MBTL1ATM | |
| SCHEMBL8204602 | 0.80 | RAB9A (0.60) | LMNARAB9AMAPTL3MBTL1NPC1 | |
| SCHEMBL25246749 | 0.79 | MEN1 (0.55) | LMNARAB9AMAPTL3MBTL1PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | disclosed |