Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13462878 | 0.83 | SMN1; SMN2 (0.58) | LMNANPC1PDE4BRAB9AKDM4E | |
| SCHEMBL23273674 | 0.83 | NPC1 (0.52) | LMNANPC1PDE4BRAB9AKDM4E | |
| SCHEMBL26102129 | 0.82 | LMNA (0.51) | LMNANPC1PDE4BRAB9AKDM4E | |
| SCHEMBL8986609 | 0.82 | RAB9A (0.48) | LMNANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL1458234 | 0.82 | LMNA (0.51) | LMNANPC1PDE4BRAB9AKDM4E | |
| SCHEMBL15273679 | 0.81 | LMNA (0.50) | LMNANPC1PDE4BRAB9AKDM4E | |
| SCHEMBL173434 | 0.81 | NPC1 (0.68) | LMNANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL23319033 | 0.81 | LMNA (0.53) | LMNANPC1PDE4BRAB9AKDM4E | |
| SCHEMBL1458310 | 0.79 | LMNA (0.49) | LMNANPC1PDE4BRAB9AKDM4E | |
| SCHEMBL14973322 | 0.78 | LMNA (0.48) | LMNANPC1PDE4BRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087780-B2 | Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof | NISSAN CHEMICAL IND LTD (JP) | 1995-02-15 | — | — | EP | disclosed |
| US-4954164-A | Pyrazolesulfonylurea derivatives, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-04 | — | — | US | disclosed |