Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.55 |
| ▸ | PGR | P06401 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | AR | P10275 | 3/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | IL5 | P05113 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743570 | 0.96 | HIF1A (0.50) | HIF1APGRCYP3A4NR3C1NR3C2 | |
| SCHEMBL2020336 | 0.88 | HIF1A (0.62) | HIF1APGRCYP3A4NR3C1NR3C2 | |
| SCHEMBL7735918 | 0.87 | ALDH1A1 (0.64) | HIF1APGRCYP3A4NR3C1NR3C2 | |
| SCHEMBL2016044 | 0.86 | NR3C1 (0.73) | HIF1APGRCYP3A4NR3C1NR3C2 | |
| SCHEMBL7741842 | 0.83 | HIF1A (0.60) | HIF1APGRCYP3A4NR3C1NR3C2 | |
| SCHEMBL2017765 | 0.82 | NR3C1 (0.57) | HIF1APGRCYP3A4NR3C1NR3C2 | |
| SCHEMBL7735905 | 0.81 | HIF1A (0.66) | HIF1APGRCYP3A4NR3C1NR3C2 | |
| SCHEMBL28106323 | 0.77 | CYP17A1 (0.72) | HIF1APGRCYP3A4NR3C1NR3C2 | |
| SCHEMBL27780950 | 0.77 | CYP17A1 (0.72) | HIF1APGRCYP3A4NR3C1NR3C2 | |
| SCHEMBL7519660 | 0.77 | HIF1A (0.75) | HIF1APGRCYP3A4NR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502092-B1 | ORAL COMPOSITION FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES | DRACO AB (SE) | 1995-07-26 | — | — | EP | claimed |
| EP-0502092-B1 | ORAL COMPOSITION FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES | DRACO AB (SE) | 1995-07-26 | — | — | EP | disclosed |