Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33148 | 0.94 | SMN1; SMN2 (0.52) | MAPK1SMN1; SMN2PDE4APDE7APOLB | |
| SCHEMBL2245306 | 0.85 | GAA (0.55) | MAPK1SMN1; SMN2PDE4APDE7APOLB | |
| SCHEMBL9197498 | 0.85 | MAPK1 (0.42) | MAPK1SMN1; SMN2PDE4APDE7APOLB | |
| SCHEMBL5913975 | 0.84 | PDE4A (0.48) | MAPK1SMN1; SMN2PDE4APDE7APOLB | |
| SCHEMBL11160381 | 0.84 | POLB (0.51) | MAPK1SMN1; SMN2PDE4APDE7APOLB | |
| SCHEMBL10922024 | 0.82 | GAA (0.51) | MAPK1SMN1; SMN2PDE4APDE7APOLB | |
| SCHEMBL9199029 | 0.82 | MAPK1 (0.41) | MAPK1SMN1; SMN2PDE4APDE7APOLB | |
| SCHEMBL2682570 | 0.80 | KMT2A (0.53) | MAPK1SMN1; SMN2PDE4APDE7ALMNA | |
| SCHEMBL29462964 | 0.80 | KMT2A (0.53) | MAPK1SMN1; SMN2PDE4APDE7ALMNA | |
| SCHEMBL9155654 | 0.80 | MAPK1 (0.42) | MAPK1SMN1; SMN2PDE4APDE7APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| US-20230346951-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | YALE UNIVERSITY | 2023-11-02 | — | — | US | disclosed |
| WO-2023091644-A2 | HSD17B13-RELATED DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023049218-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-30 | — | — | WO | disclosed |
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |
| WO-2021234459-A9 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2022-02-03 | — | — | WO | disclosed |
| WO-2021234459-A2 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |
| WO-2021237223-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |
| US-20170152253-A1 | Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV | Janssen Pharmaceuticals, Inc. (US) | 2017-06-01 | — | — | US | disclosed |
| US-9586893-B2 | Processes and intermediates for preparing a macrocyclic protease inhibitor of HCV | Janssen Pharmaceuticals (US) | 2017-03-07 | — | — | US | disclosed |
| EP-0001514-B1 | HERBICIDAL SULFONAMIDES, AND PREPARATION AND USE THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-08-08 | — | — | EP | disclosed |
| EP-0044213-B1 | N-(HETEROCYCLIC CARBAMOYL)ARYL SULFAMATES AND THEIR USE AS HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-05-16 | — | — | EP | disclosed |
| US-4443244-A | TRIAZINES AND PYRIMIDINES, PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-04-17 | — | — | US | disclosed |
| US-4394153-A | PLANT GROWTH RETARDERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-07-19 | — | — | US | disclosed |
| US-4371391-A | TRIAZIN-2-YL-AMINO CARBONYL BENZENE SURLONAMIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-02-01 | — | — | US | disclosed |
| US-4339266-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| EP-0048143-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| EP-0044213-A1 | N-(heterocyclic carbamoyl)aryl sulfamates and their use as herbicides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-20 | — | — | EP | disclosed |
| US-4257802-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| EP-0001514-A2 | Herbicidal sulfonamides, and preparation and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152253-A1 | Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV | HAVCR2, RNASE1, CPB1 | MAPK1 864/4885SMN1; SMN2 4090/4885PDE4A 4177/4885 |
| US-20230346951-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | ASGR1, MSR1, LDLR | MAPK1 2363/4885SMN1; SMN2 3100/4885PDE4A 2491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.