Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 9/20 | 0.53 |
| ▸ | MAOA | P21397 | 8/20 | 0.53 |
| ▸ | MAOB | P27338 | 8/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 14/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 14/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 14/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640503 | 0.88 | MAOA (0.54) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL9199669 | 0.84 | ADRA2B (0.64) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL9640404 | 0.84 | ADRA2B (0.65) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL9201690 | 0.82 | ADRA2B (0.67) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL7861118 | 0.81 | MAOA (0.53) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL7854252 | 0.81 | MAOA (0.59) | NISCHMAOAMAOBADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL7860436 | 0.81 | MAOA (0.52) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL3169171 | 0.81 | NISCH (0.52) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL9199785 | 0.80 | MAOA (0.52) | NISCHMAOAMAOBADRA2AADRA2B | |
| SCHEMBL7854312 | 0.79 | ADRA2B (0.50) | NISCHMAOAMAOBADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423802-B1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMA (US) | 1995-08-09 | — | — | EP | disclosed |