Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13800990 | 0.75 | ALDH1A1 (0.56) | DRD2 | |
| SCHEMBL8089839 | 0.73 | DRD2 (0.44) | DRD2GRM2OPRM1OPRL1MLYCD | |
| SCHEMBL6360683 | 0.73 | MEN1 (0.54) | SIGMAR1 | |
| SCHEMBL9207312 | 0.72 | CNR1 (0.33) | — | |
| SCHEMBL8104930 | 0.71 | GRM2 (0.45) | DRD2GRM2OPRM1OPRL1HSD11B1 | |
| SCHEMBL13800992 | 0.71 | DRD2 (0.66) | DRD2MLYCDNR1H2NR1H3GPR119 | |
| SCHEMBL17893525 | 0.71 | DRD2 (0.61) | DRD2GRM2MLYCDNR1H2NR1H3 | |
| SCHEMBL8098979 | 0.70 | GRM2 (0.44) | DRD2GRM2OPRM1OPRL1MLYCD | |
| SCHEMBL8779983 | 0.70 | DRD2 (0.64) | DRD2MLYCDNR1H2NR1H3GPR119 | |
| SCHEMBL21442594 | 0.69 | DRD2 (0.71) | DRD2MLYCDNR1H2NR1H3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |