Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 9/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098979 | 0.85 | GRM2 (0.44) | GRM2DRD2OPRM1OPRL1HSD11B1 | |
| SCHEMBL8098982 | 0.83 | ALDH1A1 (0.37) | GRM2NR1H2NR1H3 | |
| SCHEMBL8097791 | 0.81 | L3MBTL1 (0.45) | GRM2DRD2HSD11B1 | |
| SCHEMBL8105245 | 0.81 | ALDH1A1 (0.47) | DRD2 | |
| SCHEMBL8097196 | 0.79 | MGLL (0.45) | GRM2DRD2 | |
| SCHEMBL8096938 | 0.78 | FADS1 (0.44) | GRM2DRD2 | |
| SCHEMBL8090453 | 0.78 | ATM (0.48) | HSD11B1 | |
| SCHEMBL8089618 | 0.78 | FAAH (0.42) | DRD2HSD11B1 | |
| SCHEMBL8099398 | 0.78 | ALOX5 (0.42) | HSD11B1 | |
| SCHEMBL8089839 | 0.77 | DRD2 (0.44) | GRM2DRD2OPRM1OPRL1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |