Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 6/20 | 0.40 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | DRD3 | P35462 | 5/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195240 | 0.91 | LDHA (0.38) | OPRM1ESR1ESR2LDHA | |
| SCHEMBL6604120 | 0.81 | OPRK1 (0.37) | OPRK1DRD2DRD3OPRM1OPRD1 | |
| SCHEMBL9198951 | 0.80 | LDHA (0.40) | LDHA | |
| SCHEMBL6608872 | 0.76 | LDHA (0.41) | OPRM1DRD1LDHA | |
| SCHEMBL6604499 | 0.76 | MMP2 (0.40) | CNR1CNR2GPR55LDHA | |
| SCHEMBL9198735 | 0.76 | LDHA (0.41) | OPRK1DRD2DRD3OPRM1OPRD1 | |
| SCHEMBL9199813 | 0.74 | MLNR (0.41) | OPRD1ESR1ESR2DRD1 | |
| SCHEMBL6175249 | 0.74 | MLNR (0.41) | OPRM1OPRD1DRD1LDHA | |
| SCHEMBL6606915 | 0.73 | LDHA (0.47) | LDHA | |
| SCHEMBL3632231 | 0.73 | HTR2B (0.40) | OPRD1ESR1ESR2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-30 | — | — | EP | claimed |
| EP-0541798-B1 | NEW DIAMINE COMPOUND AND BRAIN PROTECTING AGENT CONTAINING THE SAME | KOWA CO (JP) | 1995-11-29 | — | — | EP | disclosed |