Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199786 | 0.91 | OPRK1 (0.40) | LDHAOPRM1ESR1ESR2 | |
| SCHEMBL9198951 | 0.88 | LDHA (0.40) | LDHAEGFRXIAPL3MBTL1ASAH1 | |
| SCHEMBL6608872 | 0.84 | LDHA (0.41) | LDHAEGFRXIAPOPRM1OPRL1 | |
| SCHEMBL9199813 | 0.82 | MLNR (0.41) | XIAPPOLBESR1ESR2PRKCA | |
| SCHEMBL6604499 | 0.81 | MMP2 (0.40) | LDHAEGFRL3MBTL1UTS2R | |
| SCHEMBL6606915 | 0.81 | LDHA (0.47) | LDHAEGFRGAAL3MBTL1UTS2R | |
| SCHEMBL6609678 | 0.80 | LDHA (0.40) | LDHAEGFROPRM1OPRL1GAA | |
| SCHEMBL6606198 | 0.80 | LDHA (0.39) | LDHAEGFRXIAPOPRM1GAA | |
| SCHEMBL6606184 | 0.80 | LDHA (0.45) | LDHAXIAPASAH1 | |
| SCHEMBL9196032 | 0.79 | PRKCA (0.39) | XIAPPOLBESR1ESR2PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-30 | — | — | EP | claimed |