SCHEMBL9200097

SCHEMBL9200097

O=C(Nc1cccc(-n2nnnc2S)c1)Oc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 8/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MAPT P10636 4/20 0.43
KDM4E B2RXH2 2/20 0.43
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
LMNA P02545 1/20 0.42
GAA P10253 3/20 0.42
HTT P42858 1/20 0.42
RAD51 Q06609 1/20 0.41
POLB P06746 1/20 0.41
USP2 O75604 1/20 0.41
FAAH O00519 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13297868 0.87 ALDH1A1 (0.52) CYP1A2KMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL4605666 0.86 CYP1A2 (0.53) CYP1A2KMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL10988061 0.85 ALDH1A1 (0.45) KMT2AALDH1A1SMN1; SMN2MAPTLMNA
SCHEMBL10986870 0.84 ALDH1A1 (0.44) KMT2AALDH1A1SMN1; SMN2MAPTLMNA
SCHEMBL14498648 0.84 TSHR (0.46) KMT2ASMN1; SMN2MAPTLMNAHTT
SCHEMBL8172135 0.84 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2MAPTLMNAGAA
SCHEMBL5669641 0.82 POLB (0.54) KMT2AKDM4EPOLB
SCHEMBL10984585 0.81 LMNA (0.50) CYP1A2KMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL10991114 0.81 HPGD (0.51) CYP1A2KMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL14498667 0.81 TP53 (0.54) KMT2AALDH1A1SMN1; SMN2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741017-B2 Silver halide color photographic light-sensitive material and image formation method using the same, silver halide emulsion, reducing compound having group adsorptive to silver halide and method for producing the same FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
US-7741017-B2 Silver halide color photographic light-sensitive material and image formation method using the same, silver halide emulsion, reducing compound having group adsorptive to silver halide and method for producing the same FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
US-20080242860-A1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL AND IMAGE FORMATION METHOD USING THE SAME, SILVER HALIDE EMULSION, REDUCING COMPOUND HAVING GROUP ADSORPTIVE TO SILVER HALIDE AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080242860-A1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL AND IMAGE FORMATION METHOD USING THE SAME, SILVER HALIDE EMULSION, REDUCING COMPOUND HAVING GROUP ADSORPTIVE TO SILVER HALIDE AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
EP-0283040-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1995-06-21 EP disclosed
US-5294709-A Methine compounds and methine dyes FUJI PHOTO FILM CO., LTD. (JP) 1994-03-15 US disclosed
US-5100761-A Acylhydrazine compounds, high contrast, storage stability FUJI PHOTO FILM CO., LTD. (JP) 1992-03-31 US disclosed
US-5032500-A Adding sensitizing dye containing for inhibitor after grain formation and before ripening FUJI PHOTO FILM CO., LTD. (JP) 1991-07-16 US disclosed
EP-0283040-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-09-21 EP disclosed
US-4770991-A HIGH SPEED GIVING HIGH CONTRAST AND HIGH MAXIMUM DENSITY IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1988-09-13 US disclosed
US-4554246-A THIOTETREAZOLYLPHENYL CARBAMATE FUJI PHOTO FILM CO., LTD. (JP) 1985-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242860-A1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL AND IMAGE FORMATION METHOD USING THE SAME, SILVER HALIDE EMULSION, REDUCING COMPOUND HAVING GROUP ADSORPTIVE TO SILVER HALIDE AND METHOD FOR PRODUCING THE SAME IK, APOL1, CLTA CYP1A2 1685/4885KMT2A 2457/4885ALDH1A1 349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.