Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196039 | 0.91 | PPARG (0.61) | AGTR1AGTR2PPARG | |
| SCHEMBL9195908 | 0.84 | PPARG (0.61) | AGTR1AGTR2PPARG | |
| SCHEMBL9443092 | 0.84 | PPARG (0.68) | AGTR1AGTR2PPARG | |
| SCHEMBL9638129 | 0.84 | PPARG (0.57) | AGTR1AGTR2PPARG | |
| SCHEMBL9122418 | 0.83 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL27528971 | 0.82 | PPARG (0.55) | AGTR1AGTR2PPARG | |
| SCHEMBL9442986 | 0.82 | EDNRA (0.54) | AGTR1AGTR2PPARG | |
| SCHEMBL9442999 | 0.81 | PPARG (0.50) | PPARG | |
| SCHEMBL9847764 | 0.80 | PPARG (0.55) | AGTR1AGTR2PPARG | |
| SCHEMBL9847780 | 0.79 | PPARG (0.56) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425921-B1 | Benzimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5128356-A | Angiotensin antagonist; cardiovascular disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0425921-A1 | Benzimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-05-08 | — | — | EP | disclosed |