Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199997 | 0.91 | PPARG (0.64) | EDNRAPPARGAGTR1AGTR2 | |
| SCHEMBL9443092 | 0.86 | PPARG (0.68) | PPARGAGTR1AGTR2 | |
| SCHEMBL9638129 | 0.85 | PPARG (0.57) | EDNRAPPARGAGTR1AGTR2 | |
| SCHEMBL27528971 | 0.84 | PPARG (0.55) | PPARGAGTR1AGTR2 | |
| SCHEMBL9193540 | 0.84 | PPARG (0.64) | EDNRAPPARGAGTR1AGTR2 | |
| SCHEMBL9200218 | 0.82 | AGTR1 (0.52) | PPARGAGTR1AGTR2 | |
| SCHEMBL9847764 | 0.81 | PPARG (0.55) | PPARGAGTR1AGTR2 | |
| SCHEMBL9847780 | 0.81 | PPARG (0.56) | PPARGAGTR1AGTR2 | |
| SCHEMBL27361797 | 0.78 | TLR7 (0.50) | PPARGAGTR1AGTR2TLR7 | |
| SCHEMBL9851425 | 0.77 | AGTR1 (0.56) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1029961-C | Benzimidazole derivatives, their prodn. and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-10-11 | — | — | CN | disclosed |
| US-5250554-A | Cardiovascular disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| CN-1051355-A | Benzimidizole derivatives, its production method and application thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1991-05-15 | — | — | CN | disclosed |