Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201648 | 0.91 | ALDH1A1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL9202020 | 0.78 | ALDH1A1 (0.44) | ADORA3ADORA2AADORA1KMT2APOLB | |
| SCHEMBL9198235 | 0.77 | ADORA3 (0.36) | ADORA3ADORA2AADORA1KMT2APOLB | |
| SCHEMBL9141210 | 0.75 | ADORA3 (0.34) | ADORA3ADORA2AADORA1KMT2APOLB | |
| SCHEMBL9200290 | 0.74 | POLB (0.36) | ADORA3ADORA2AADORA1KMT2APOLB | |
| SCHEMBL30296175 | 0.73 | GLA (0.34) | ADORA3ADORA2AADORA1POLBKDM4C | |
| SCHEMBL9200090 | 0.73 | ALDH1A1 (0.34) | KMT2AAGTR1AGTR2 | |
| SCHEMBL9137917 | 0.72 | HPGD (0.43) | AGTR1AGTR2 | |
| SCHEMBL4356818 | 0.71 | GLA (0.35) | ADORA3ADORA2AADORA1KMT2APOLB | |
| SCHEMBL9205499 | 0.70 | PARP1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643709-A1 | 4-(1-$i(H)-PYRROL-1-YL)IMIDAZOLES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1995-03-22 | — | — | EP | claimed |
| US-5210211-A | 4-(1H-PYRROL-1-YL) IMIDAZOLES WITH ANGIOTENSION II ANTAGONIST ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1993-05-11 | — | — | US | claimed |
| WO-1993000341-A1 | 4-(1-H-PYRROL-1-YL)IMIDAZOLES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1993-01-07 | — | — | WO | claimed |
| EP-0643709-A1 | 4-(1-$i(H)-PYRROL-1-YL)IMIDAZOLES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1995-03-22 | — | — | EP | disclosed |
| US-5276048-A | 4-(1H-pyrrol-1-yl)imidazoles with angiotensin II antagonist activity | WARNER-LAMBERT COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| US-5210211-A | 4-(1H-PYRROL-1-YL) IMIDAZOLES WITH ANGIOTENSION II ANTAGONIST ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| WO-1993000341-A1 | 4-(1-H-PYRROL-1-YL)IMIDAZOLES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1993-01-07 | — | — | WO | disclosed |