Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 1/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | CCKBR | P32239 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 5/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 2/20 | 0.39 |
| ▸ | PYGM | P11217 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200567 | 1.00 | UBE2M (0.46) | UBE2MDCUN1D1TAS1R3TAS1R1CCKBR | |
| SCHEMBL9200559 | 1.00 | UBE2M (0.46) | UBE2MDCUN1D1TAS1R3TAS1R1CCKBR | |
| SCHEMBL9206950 | 0.89 | LMNA (0.50) | CCKBRF10LMNATP53 | |
| SCHEMBL9206977 | 0.89 | LMNA (0.50) | CCKBRF10LMNATP53 | |
| SCHEMBL9206962 | 0.89 | LMNA (0.50) | CCKBRF10LMNATP53 | |
| SCHEMBL9205891 | 0.87 | CCKBR (0.54) | CCKBR | |
| SCHEMBL9205875 | 0.87 | CCKBR (0.54) | CCKBR | |
| SCHEMBL9205881 | 0.87 | CCKBR (0.54) | CCKBR | |
| SCHEMBL9206749 | 0.86 | CCKBR (0.58) | UBE2MDCUN1D1TAS1R3CCKBRF10 | |
| SCHEMBL9198246 | 0.86 | CCKBR (0.58) | UBE2MDCUN1D1TAS1R3CCKBRF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561941-B1 | N-SUBSTITUTED LACTAMS USEFUL AS CHOLECYSTOKININ ANTAGONISTS | SEARLE & CO (US) | 1995-01-04 | — | — | EP | disclosed |
| US-5314886-A | N-substituted lactams useful as cholecystokinin antagonists | G. D. SEARLE & CO. (US) | 1994-05-24 | — | — | US | disclosed |
| US-5202344-A | Disorders of the gastrointestinal, central nervous system and appetite regulatory systems | G. D. SEARLE & CO. (US) | 1993-04-13 | — | — | US | disclosed |