SCHEMBL9200671

SCHEMBL9200671

Cc1nn(C)c(C(=O)N(C)C)c1S(N)(=O)=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.37
ALDH1A1 P00352 3/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
HPGD P15428 2/20 0.32
HSD17B10 Q99714 2/20 0.32
CA1 P00915 4/20 0.32
CA2 P00918 4/20 0.32
CA12 O43570 2/20 0.32
CA4 P22748 2/20 0.32
CA6 P23280 2/20 0.32
CA5A P35218 2/20 0.32
CA7 P43166 2/20 0.32
CA9 Q16790 2/20 0.32
CA14 Q9ULX7 2/20 0.32
CA5B Q9Y2D0 2/20 0.32
CA3 P07451 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9274977 0.81 KDM4E (0.40) KDM4EALDH1A1NPSR1SMN1; SMN2HPGD
SCHEMBL9200764 0.77 HPGD (0.50) KDM4EALDH1A1NPSR1SMN1; SMN2HPGD
SCHEMBL10915710 0.76 KDM4E (0.41) KDM4EALDH1A1SMN1; SMN2GAA
SCHEMBL9201714 0.75 ALDH1A1 (0.45) KDM4EALDH1A1NPSR1SMN1; SMN2HPGD
SCHEMBL10475093 0.74 ALDH1A1 (0.36) KDM4EALDH1A1NPSR1SMN1; SMN2HPGD
SCHEMBL28327562 0.72 CA12 (0.35) KDM4EALDH1A1NPSR1HPGDHSD17B10
SCHEMBL3376273 0.71 TSHR (0.44) KDM4EALDH1A1NPSR1SMN1; SMN2CA1
SCHEMBL15353484 0.70 CA1 (0.47) KDM4EALDH1A1NPSR1HPGDHSD17B10
SCHEMBL9198130 0.70 CDK1 (0.33) KDM4EGAA
SCHEMBL1626536 0.68 L3MBTL1 (0.42) KDM4ECA1CA2CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0087780-B2 Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL IND LTD (JP) 1995-02-15 EP disclosed
US-4954164-A Pyrazolesulfonylurea derivatives, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1990-09-04 US disclosed
EP-0087780-A2 Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1983-09-07 EP disclosed