Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.64 |
| ▸ | PRKCA | P17252 | 7/20 | 0.62 |
| ▸ | CDK4 | P11802 | 9/20 | 0.61 |
| ▸ | CCND1 | P24385 | 9/20 | 0.61 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.61 |
| ▸ | PRKCG | P05129 | 4/20 | 0.61 |
| ▸ | PRKCB | P05771 | 4/20 | 0.61 |
| ▸ | PRKCH | P24723 | 4/20 | 0.61 |
| ▸ | PRKCI | P41743 | 4/20 | 0.61 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.61 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.61 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.61 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.61 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.61 |
| ▸ | PRKACA | P17612 | 3/20 | 0.61 |
| ▸ | PRKACG | P22612 | 3/20 | 0.61 |
| ▸ | PRKACB | P22694 | 3/20 | 0.61 |
| ▸ | CAMK2B | Q13554 | 6/20 | 0.50 |
| ▸ | CAMK2G | Q13555 | 6/20 | 0.50 |
| ▸ | CAMK2D | Q13557 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22765176 | 0.86 | PRKCA (0.80) | ROCK2PRKCACDK4CCND1PRKD3 | |
| SCHEMBL9196626 | 0.76 | CDK4 (1.00) | ROCK2PRKCACDK4CCND1PRKD3 | |
| SCHEMBL24853081 | 0.70 | PRKCA (0.58) | ROCK2PRKCACDK4CCND1PRKD3 | |
| Staurosporine Aglycon SCHEMBL8124103 | 0.68 | CDK4 (1.00) | ROCK2PRKCACDK4CCND1PRKD3 | |
| Staurosporine Aglycon SCHEMBL30530825 | 0.68 | CDK4 (1.00) | ROCK2PRKCACDK4CCND1PRKD3 | |
| Staurosporine Aglycon SCHEMBL29406635 | 0.68 | CDK4 (1.00) | ROCK2PRKCACDK4CCND1PRKD3 | |
| SCHEMBL14525822 | 0.65 | CDK4 (0.58) | ROCK2PRKCACDK4CCND1PRKD3 | |
| SCHEMBL5438544 | 0.65 | PRKCA (0.71) | ROCK2PRKCACDK4CCND1PRKD3 | |
| SCHEMBL12845915 | 0.64 | CDK4 (0.64) | PRKCACDK4CCND1PRKD3PRKCG | |
| SCHEMBL14708731 | 0.63 | CDK4 (0.80) | ROCK2PRKCACDK4CCND1PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993024490-A1 | USE OF INDOLOCARBAZOLS IN AIDS TREATMENT | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | claimed |
| US-5438050-A | Indolocarbazole derivatives, processes for their preparation and compositions containing them | GODECKE AKTIENGESELLSCHAFT (DE) | 1995-08-01 | — | — | US | disclosed |
| EP-0328000-B1 | Indolocarbazole derivatives, process for their preparation and medicines containing same | GOEDECKE AG (DE) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993024490-A1 | USE OF INDOLOCARBAZOLS IN AIDS TREATMENT | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | disclosed |
| EP-0328000-A2 | Indolocarbazole derivatives, process for their preparation and medicines containing same | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1989-08-16 | — | — | EP | disclosed |