Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 7/20 | 0.71 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.66 |
| ▸ | CDK4 | P11802 | 7/20 | 0.62 |
| ▸ | CCND1 | P24385 | 7/20 | 0.62 |
| ▸ | CAMK2B | Q13554 | 4/20 | 0.62 |
| ▸ | CAMK2G | Q13555 | 4/20 | 0.62 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.62 |
| ▸ | CAMK2A | Q9UQM7 | 4/20 | 0.62 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.62 |
| ▸ | PRKCG | P05129 | 3/20 | 0.62 |
| ▸ | PRKCB | P05771 | 3/20 | 0.62 |
| ▸ | PRKACA | P17612 | 3/20 | 0.62 |
| ▸ | PRKACG | P22612 | 3/20 | 0.62 |
| ▸ | PRKACB | P22694 | 3/20 | 0.62 |
| ▸ | PRKCH | P24723 | 3/20 | 0.62 |
| ▸ | PRKCI | P41743 | 3/20 | 0.62 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.62 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.62 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14708732 | 0.90 | ROCK2 (0.58) | PRKCAROCK2CDK4CCND1CAMK2B | |
| SCHEMBL5440800 | 0.87 | CDK4 (0.70) | PRKCAROCK2CDK4CCND1CAMK2B | |
| SCHEMBL6080907 | 0.85 | PRKCA (0.57) | PRKCAROCK2CDK4CCND1CAMK2B | |
| SCHEMBL8122606 | 0.84 | CDK4 (0.77) | PRKCAROCK2CDK4CCND1CAMK2B | |
| SCHEMBL16504230 | 0.83 | CDK4 (0.60) | PRKCAROCK2CDK4CCND1NQO1 | |
| SCHEMBL14498911 | 0.83 | ROCK2 (0.55) | PRKCAROCK2CDK4CCND1CAMK2B | |
| SCHEMBL8317372 | 0.83 | PRKCA (1.00) | PRKCAROCK2CDK4CCND1CAMK2B | |
| SCHEMBL17682020 | 0.81 | NQO1 (0.53) | PRKCAROCK2CDK4CCND1CAMK2B | |
| SCHEMBL8318191 | 0.80 | PRKCA (0.67) | PRKCAROCK2CDK4CCND1CAMK2B | |
| SCHEMBL6080838 | 0.79 | ROCK2 (0.48) | PRKCAROCK2CDK4CCND1CAMK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630242-B1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | WELLCOME FOUND (GB) | 1999-01-20 | — | — | EP | claimed |
| US-9508938-B2 | Organic compound and photovoltaic device comprising the same | CRYSCADE SOLAR LIMITED (CY) | 2016-11-29 | — | — | US | disclosed |
| US-20160043328-A1 | ORGANIC COMPOUND AND PHOTOVOLTAIC DEVICE COMPRISING THE SAME | CRYSCADE SOLAR LIMITED (CY) | 2016-02-11 | — | — | US | disclosed |
| US-9193727-B2 | Organic compound and photovoltaic device comprising the same | CRYSCADE SOLAR LIMITED (CY) | 2015-11-24 | — | — | US | disclosed |
| US-20120227802-A1 | ORGANIC COMPOUND AND PHOTOVOLTAIC DEVICE COMPRISING THE SAME | CRYSCADE SOLAR LIMITED (CY) | 2012-09-13 | — | — | US | disclosed |
| US-20070249590-A1 | Substituted indolo[2,3-a]pyrrolo[3,4-c]carbazole compounds useful in treating kinase disorders | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-10-25 | — | — | US | disclosed |
| US-20070249590-A1 | Substituted indolo[2,3-a]pyrrolo[3,4-c]carbazole compounds useful in treating kinase disorders | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-10-25 | — | — | US | disclosed |
| US-20070249590-A1 | Substituted indolo[2,3-a]pyrrolo[3,4-c]carbazole compounds useful in treating kinase disorders | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-10-25 | — | — | US | disclosed |
| US-7227019-B2 | Process for the preparation of rebeccamycin and analogs thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-06-05 | — | — | US | disclosed |
| EP-0642513-B1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | KTB TUMORFORSCHUNGSGESELLSCHAF (DE) | 2000-08-09 | — | — | EP | disclosed |
| US-5945440-A | Indolocarbazole imides and the use thereof | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | disclosed |
| US-5883114-A | TREATING CANCEROUS TUMORS, INFLAMMATORY DISEASES, AND ALLERGIES | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |
| EP-0642513-A1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993024491-A1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160043328-A1 | ORGANIC COMPOUND AND PHOTOVOLTAIC DEVICE COMPRISING THE SAME | CORO1C, SUN2, VDAC1 | PRKCA 3165/4885ROCK2 659/4885CDK4 1633/4885 |
| US-20070249590-A1 | Substituted indolo[2,3-a]pyrrolo[3,4-c]carbazole compounds useful in treating kinase disorders | PRKACA, PRKDC, PACSIN2 | PRKCA 29/4885ROCK2 424/4885CDK4 129/4885 |
| US-20120227802-A1 | ORGANIC COMPOUND AND PHOTOVOLTAIC DEVICE COMPRISING THE SAME | SUN2, CORO1C, CORO1A | PRKCA 4668/4885ROCK2 751/4885CDK4 1552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.