Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932465 | 0.70 | NPC1 (0.40) | MAPTLMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL8932491 | 0.70 | LMNA (0.39) | MAPTLMNATP53PTGIRMEN1 | |
| SCHEMBL8307284 | 0.70 | TDP1 (0.50) | APPIDO1CRBNMEN1KMT2A | |
| SCHEMBL8932476 | 0.70 | APP (0.44) | APPIDO1TP53CRBNSMN1; SMN2 | |
| SCHEMBL7833142 | 0.69 | KMT2A (0.55) | NPC1RAB9AAPPIDO1KMT2A | |
| Hydrochloric Acid SCHEMBL10506096 | 0.69 | IDO1 (0.40) | APPIDO1KMT2A | |
| SCHEMBL9202656 | 0.69 | TSHR (0.46) | MAPTLMNAAPPIDO1CRBN | |
| SCHEMBL8932561 | 0.69 | APP (0.36) | MAPTLMNAMAPK1NPC1RAB9A | |
| SCHEMBL9480021 | 0.68 | REN (0.44) | APPIDO1CRBNSMN1; SMN2 | |
| SCHEMBL8932409 | 0.68 | APP (0.42) | APPIDO1TP53CRBNSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210883-B1 | Derivatives of penem | DAIICHI SEIYAKU CO (JP) | 1995-02-01 | — | — | EP | disclosed |
| US-5079357-A | Bactericides | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| US-4962202-A | PENICILLIN INTERMEDIATES | DAIICHI SEIYAKU CO., LTD. (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0210883-A2 | Derivatives of penem | DAIICHI SEIYAKU CO., LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |