Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932546 | 0.85 | CRBN (0.44) | APPIDO1CRBNMAOAMAOB | |
| SCHEMBL8932476 | 0.81 | APP (0.44) | APPALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL9202656 | 0.79 | TSHR (0.46) | APPALDH1A1TSHRIDO1CRBN | |
| SCHEMBL8932477 | 0.78 | MAOB (0.40) | APPALDH1A1IDO1CRBNMAOA | |
| SCHEMBL8932411 | 0.78 | BCHE (0.39) | APPTSHRSMN1; SMN2IDO1CRBN | |
| SCHEMBL8932463 | 0.77 | NAAA (0.40) | ALDH1A1CYP3A4SMN1; SMN2IDO1CRBN | |
| SCHEMBL8932509 | 0.76 | TP53 (0.40) | APPALDH1A1TP53SMN1; SMN2IDO1 | |
| SCHEMBL8932562 | 0.76 | GSK3B (0.37) | APPALDH1A1CYP3A4TSHRIDO1 | |
| SCHEMBL9480021 | 0.76 | REN (0.44) | APPALDH1A1SMN1; SMN2IDO1CRBN | |
| SCHEMBL8307284 | 0.75 | TDP1 (0.50) | APPALDH1A1SMN1; SMN2IDO1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026939-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-06 | — | — | WO | disclosed |