Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 3/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315810 | 0.85 | TP53 (0.36) | LMNAMEN1KMT2ACYP2C9CYP3A4 | |
| SCHEMBL9202387 | 0.83 | GABBR2 (0.51) | GABBR2GABBR1LMNAMEN1KMT2A | |
| SCHEMBL9201733 | 0.76 | ALOX5 (0.43) | GABBR2GABBR1LMNAMEN1KMT2A | |
| SCHEMBL657859 | 0.75 | HSD17B10 (0.39) | GABBR2GABBR1LMNAMEN1KMT2A | |
| SCHEMBL9315762 | 0.73 | MAPT (0.35) | LMNAMEN1KMT2ATSHRMAPT | |
| SCHEMBL9988481 | 0.72 | GABBR2 (0.61) | GABBR2GABBR1LMNAMEN1KMT2A | |
| SCHEMBL27725190 | 0.72 | GABBR2 (0.61) | GABBR2GABBR1LMNAMEN1KMT2A | |
| SCHEMBL21686411 | 0.72 | GABBR2 (0.61) | GABBR2GABBR1LMNAMEN1KMT2A | |
| SCHEMBL9315930 | 0.71 | MAPT (0.34) | LMNAMEN1KMT2ACYP2C9CYP1A2 | |
| SCHEMBL9315021 | 0.70 | KDM4E (0.38) | LMNACYP2C19MAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463969-B1 | New compounds of 4-aminobutyric acid, process for their preparation and pharmaceutical preparations containing them | ADIR (FR) | 1995-02-08 | — | — | EP | disclosed |
| EP-0463969-A1 | New compounds of 4-aminobutyric acid, process for their preparation and pharmaceutical preparations containing them | ADIR ET COMPAGNIE (FR) | 1992-01-02 | — | — | EP | disclosed |