Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315814 | 0.84 | TP53 (0.48) | ALOX5KDM4ECYP2C9ALDH1A1CYP1A2 | |
| SCHEMBL9202393 | 0.82 | GABBR2 (0.54) | ALOX5KDM4ECYP2C9ALDH1A1CYP1A2 | |
| SCHEMBL9201731 | 0.76 | GABBR2 (0.35) | CYP2C9ALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL27725190 | 0.74 | GABBR2 (0.61) | CYP2C9ALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL21686411 | 0.74 | GABBR2 (0.61) | CYP2C9ALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL9988481 | 0.74 | GABBR2 (0.61) | CYP2C9ALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL657858 | 0.74 | KMT2A (0.48) | ALOX5KDM4ECYP2C9ALDH1A1CYP1A2 | |
| SCHEMBL9315765 | 0.71 | TAS1R3 (0.41) | KDM4EALDH1A1MAOBMMP2MMP9 | |
| SCHEMBL9315934 | 0.70 | KDM4E (0.39) | KDM4EALDH1A1L3MBTL1MAOBTSHR | |
| SCHEMBL9315905 | 0.70 | CA12 (0.42) | KDM4EALDH1A1MAOBTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463969-B1 | New compounds of 4-aminobutyric acid, process for their preparation and pharmaceutical preparations containing them | ADIR (FR) | 1995-02-08 | — | — | EP | disclosed |
| EP-0463969-A1 | New compounds of 4-aminobutyric acid, process for their preparation and pharmaceutical preparations containing them | ADIR ET COMPAGNIE (FR) | 1992-01-02 | — | — | EP | disclosed |