Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 4/20 | 0.61 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | FNTA | P49354 | 4/20 | 0.47 |
| ▸ | FNTB | P49356 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27725190 | 1.00 | GABBR2 (0.61) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL21686411 | 1.00 | GABBR2 (0.61) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL27165024 | 0.86 | GABBR2 (0.44) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL27204614 | 0.86 | GABBR2 (0.44) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL29147714 | 0.85 | GABBR2 (0.58) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL22831452 | 0.85 | GABBR2 (0.58) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL15389394 | 0.84 | ALDH1A1 (0.48) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL21686319 | 0.84 | SERPINH1 (0.43) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL22831458 | 0.84 | L3MBTL1 (0.49) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL22831460 | 0.84 | L3MBTL1 (0.49) | GABBR2GABBR1CYP2C9LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273917-B2 | Method for preparing chiral baclofen | SCI PHARMTECH, INC. (TW) | 2012-09-25 | — | — | US | disclosed |
| US-8273917-B2 | Method for preparing chiral baclofen | SCI PHARMTECH, INC. (TW) | 2012-09-25 | — | — | US | disclosed |
| US-20120029230-A1 | METHOD FOR PREPARING CHIRAL BACLOFEN | SCI PHARMTECH, INC. (TW) | 2012-02-02 | — | — | US | disclosed |
| US-20120029230-A1 | METHOD FOR PREPARING CHIRAL BACLOFEN | SCI PHARMTECH, INC. (TW) | 2012-02-02 | — | — | US | disclosed |
| CN-101333168-B | Novel method for synthesizing chiral beta-aryl-gamma-aminobutyric acid compounds | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2012-02-01 | — | — | CN | disclosed |
| CN-101333168-A | Novel method for synthesizing chiral beta-aryl-gamma-aminobutyric acid compounds | UNIV EAST CHINA SCIENCE & TECH (CN) | 2008-12-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029230-A1 | METHOD FOR PREPARING CHIRAL BACLOFEN | GABRE, GABRB2, GABRB3 | GABBR2 5/4885GABBR1 7/4885CYP2C9 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.