Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 16/20 | 0.65 |
| ▸ | HTR2A | P28223 | 10/20 | 0.65 |
| ▸ | HTR2C | P28335 | 9/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325762 | 0.87 | AKR1B1 (0.64) | SLC6A4HTR2AHTR2CAKR1B1 | |
| SCHEMBL5009470 | 0.79 | SLC6A4 (1.00) | SLC6A4HTR2AHTR2C | |
| SCHEMBL9277880 | 0.77 | ALDH1A1 (0.62) | SLC6A4HTR2AHTR2CRECQLALDH1A1 | |
| SCHEMBL9198976 | 0.75 | AKR1B1 (0.78) | SLC6A4HTR2AHTR2CRECQLALDH1A1 | |
| SCHEMBL5014224 | 0.74 | RECQL (0.83) | SLC6A4HTR2AHTR2CRECQLALDH1A1 | |
| SCHEMBL9199872 | 0.74 | AKR1B1 (0.79) | SLC6A4HTR2AHTR2CRECQLALDH1A1 | |
| SCHEMBL8201334 | 0.73 | AKR1B1 (0.78) | AKR1B1 | |
| SCHEMBL5009469 | 0.73 | RECQL (0.81) | SLC6A4HTR2AHTR2CRECQLALDH1A1 | |
| SCHEMBL9197789 | 0.73 | RECQL (0.81) | SLC6A4RECQLALDH1A1SMN1; SMN2AKR1B1 | |
| SCHEMBL9328064 | 0.72 | RECQL (0.53) | SLC6A4HTR2AHTR2CRECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436307-B1 | Substituted oxophthalazinyl acetic acids and analogs thereof | PFIZER (US) | 1995-02-22 | — | — | EP | disclosed |