SCHEMBL920197

SCHEMBL920197

CCCCCc1ccc(CNC(=O)c2cccnc2N)cc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 5/20 0.56
HPGD P15428 4/20 0.51
KDR P35968 1/20 0.49
LMNA P02545 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KMT2A Q03164 1/20 0.47
PLK1 P53350 1/20 0.47
SPHK1 Q9NYA1 1/20 0.46
NSD2 O96028 1/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
PRKCI P41743 1/20 0.45
MAPK8 P45983 1/20 0.44
ATM Q13315 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922409 0.99 TRPV1 (0.55) TRPV1HPGDKDRLMNASMN1; SMN2
SCHEMBL920973 0.99 TRPV1 (0.55) TRPV1HPGDKDRLMNASMN1; SMN2
SCHEMBL921173 0.96 KDR (0.53) TRPV1HPGDKDRLMNASMN1; SMN2
SCHEMBL920908 0.93 HPGD (0.52) TRPV1HPGDKDRLMNASMN1; SMN2
SCHEMBL922505 0.91 HPGD (0.54) HPGDLMNASMN1; SMN2KMT2ANSD2
SCHEMBL919825 0.90 HPGD (0.53) TRPV1HPGDKDRLMNASMN1; SMN2
SCHEMBL922724 0.90 TRPV1 (0.50) TRPV1HPGDLMNASMN1; SMN2KMT2A
SCHEMBL921484 0.89 TRPV1 (0.49) TRPV1HPGDLMNAKMT2ANSD2
SCHEMBL922835 0.87 LMNA (0.56) HPGDLMNASMN1; SMN2MAPK8
SCHEMBL920132 0.87 LMNA (0.58) HPGDLMNASMN1; SMN2KMT2AMAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 TRPV1 2237/4885HPGD 1273/4885KDR 4652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.