SCHEMBL920908

SCHEMBL920908

CCCCCc1ccc(Oc2ccc(CNC(=O)c3cccnc3N)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.52
LMNA P02545 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MAPK8 P45983 1/20 0.50
TRPV1 Q8NER1 1/20 0.50
EGLN1 Q9GZT9 1/20 0.45
KDR P35968 1/20 0.45
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919825 0.97 HPGD (0.53) HPGDLMNASMN1; SMN2MAPK8TRPV1
SCHEMBL920197 0.93 TRPV1 (0.56) HPGDLMNASMN1; SMN2MAPK8TRPV1
SCHEMBL919769 0.92 HPGD (0.55) HPGDLMNASMN1; SMN2MAPK8EGLN1
SCHEMBL920973 0.92 TRPV1 (0.55) HPGDLMNASMN1; SMN2TRPV1KDR
SCHEMBL922409 0.92 TRPV1 (0.55) HPGDLMNASMN1; SMN2TRPV1KDR
SCHEMBL921937 0.92 MAPK8 (0.50) HPGDLMNASMN1; SMN2MAPK8TRPV1
SCHEMBL922146 0.91 LMNA (0.55) HPGDLMNASMN1; SMN2MAPK8EGLN1
SCHEMBL921173 0.90 KDR (0.53) HPGDLMNASMN1; SMN2MAPK8TRPV1
SCHEMBL919652 0.89 MAPK8 (0.51) HPGDLMNASMN1; SMN2MAPK8MEN1
SCHEMBL920953 0.88 MAPK8 (0.47) HPGDLMNASMN1; SMN2MAPK8MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885LMNA 4812/4885SMN1; SMN2 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.