Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 8/20 | 0.59 |
| ▸ | SRC | P12931 | 8/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.51 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201027 | 0.93 | KDM4E (0.59) | ABL1SRCSMN1; SMN2KDM4ELMNA | |
| SCHEMBL9202116 | 0.90 | KDM4E (0.51) | ABL1SRCSMN1; SMN2KDM4ELMNA | |
| SCHEMBL9207418 | 0.84 | ALDH1A1 (0.49) | SMN1; SMN2KDM4ELMNAHTTHSP90AA1 | |
| SCHEMBL9203437 | 0.82 | ABL1 (0.60) | ABL1SRCSMN1; SMN2KDM4ELMNA | |
| SCHEMBL9203908 | 0.81 | MAPT (0.62) | SMN1; SMN2KDM4ELMNAHTTMAPT | |
| SCHEMBL9205774 | 0.77 | RAB9A (0.53) | SMN1; SMN2KDM4ELMNAALDH1A1 | |
| SCHEMBL9202732 | 0.77 | CA12 (0.51) | SMN1; SMN2KDM4ELMNAHTTMAPT | |
| SCHEMBL7640498 | 0.77 | CA12 (0.51) | SMN1; SMN2KDM4ELMNAHTTMAPT | |
| SCHEMBL9203435 | 0.77 | NPC1 (0.59) | ABL1SMN1; SMN2LMNAMAPTTDP1 | |
| SCHEMBL9207001 | 0.77 | NPC1 (0.56) | SMN1; SMN2KDM4ELMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550493-B1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS | UPJOHN CO (US) | 1995-08-09 | — | — | EP | claimed |
| EP-0550493-A1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1993-07-14 | — | — | EP | claimed |
| WO-1992006083-A1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-04-16 | — | — | WO | claimed |