Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.48 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 7/20 | 0.48 |
| ▸ | SRC | P12931 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201027 | 0.93 | KDM4E (0.59) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9202008 | 0.90 | ABL1 (0.59) | KDM4ESMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL9207418 | 0.86 | ALDH1A1 (0.49) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9203437 | 0.83 | ABL1 (0.60) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9203908 | 0.82 | MAPT (0.62) | KDM4ESMN1; SMN2ALDH1A1MAPTTHRB | |
| SCHEMBL9205774 | 0.78 | RAB9A (0.53) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9202732 | 0.78 | CA12 (0.51) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7640498 | 0.78 | CA12 (0.51) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9203435 | 0.77 | NPC1 (0.59) | SMN1; SMN2MEN1KMT2AALDH1A1RECQL | |
| SCHEMBL9208681 | 0.77 | CA12 (0.50) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550493-B1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS | UPJOHN CO (US) | 1995-08-09 | — | — | EP | claimed |
| WO-1992006083-A1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-04-16 | — | — | WO | claimed |