SCHEMBL920239

SCHEMBL920239

CC(C)C(C)c1cccc(Oc2ccc(CNC(=O)c3cccnc3N)cc2)c1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 1/20 0.48
HPGD P15428 3/20 0.45
LMNA P02545 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
KMT2A Q03164 2/20 0.43
POLB P06746 2/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
EGLN1 Q9GZT9 1/20 0.42
PIK3CD O00329 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919967 0.92 MAPK8 (0.50) MAPK8HPGDLMNASMN1; SMN2KMT2A
SCHEMBL920635 0.91 MAPK8 (0.50) MAPK8HPGDLMNASMN1; SMN2KMT2A
SCHEMBL921943 0.89 MAPK8 (0.48) MAPK8HPGDLMNASMN1; SMN2KMT2A
SCHEMBL920081 0.88 MAPK8 (0.46) MAPK8HPGDLMNASMN1; SMN2KMT2A
SCHEMBL3400139 0.87 PTGER4 (0.47) MAPK8HPGDSMN1; SMN2ALDH1A1
SCHEMBL919827 0.86 MAPK14 (0.42) HPGDALDH1A1
SCHEMBL921620 0.85 MAPK8 (0.52) MAPK8HPGDLMNASMN1; SMN2KMT2A
SCHEMBL920564 0.85 HPGD (0.53) MAPK8HPGDLMNAKMT2APOLB
SCHEMBL920714 0.85 MAPK8 (0.53) MAPK8HPGDLMNASMN1; SMN2KMT2A
SCHEMBL921271 0.85 HPGD (0.57) MAPK8HPGDLMNASMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAPK8 2313/4885HPGD 1273/4885LMNA 4812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.