SCHEMBL920273

SCHEMBL920273

C=CCC1c2ccccc2Oc2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
ATM Q13315 1/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 1/20 0.40
USP2 O75604 1/20 0.39
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28711286 0.85 MAOA (0.37) MAOAMAOBATMMEN1KMT2A
SCHEMBL7168957 0.80 MAOA (0.33) MAOAMAOBLMNACYP2C9
SCHEMBL12122139 0.80 MAOA (0.47) MAOAMAOBATMMEN1KMT2A
SCHEMBL252162 0.77 HTR2A (0.52) TSHR
SCHEMBL1323794 0.77 MAOA (0.52) MAOAMAOBATMMEN1KMT2A
SCHEMBL4345108 0.75 ALDH1A1 (0.40) MAPT
Hydrochloric Acid SCHEMBL21483619 0.75 MAOA (0.50) MAOAMAOBATMMEN1KMT2A
SCHEMBL4667689 0.72 HTR2A (0.58) MAOAMAOBATMMEN1KMT2A
SCHEMBL2736396 0.72 MAOA (0.52) MAOAMAOBATMMEN1KMT2A
SCHEMBL7452862 0.72 MAOA (0.52) MAOAMAOBATMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0642483-B1 CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF DOW CHEMICAL CO (US) 1998-02-18 EP claimed
EP-0642483-A4 CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF. 1995-04-19 EP claimed
EP-0642483-A1 CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF THE DOW CHEMICAL COMPANY (US) 1995-03-15 EP claimed
US-5227560-A Vinylene or exomethylene groups from active methine compounds THE DOW CHEMICAL COMPANY (US) 1993-07-13 US claimed
WO-1993009078-A1 CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF THE DOW CHEMICAL COMPANY (US) 1993-05-13 WO claimed
CN-118103773-A High refractive index photoresist composition 美国陶氏有机硅公司 2024-05-28 CN disclosed
CN-110268328-B Blue photosensitive resin composition, color filter and image display device manufactured by using the same 东友精细化工有限公司 2022-02-08 CN disclosed
US-8017620-B2 Dutpase inhibitors MEDIVIR AB (SE) 2011-09-13 US disclosed
US-20110021459-A1 DUTPASE INHIBITORS MEDIVIR AB (SE) 2011-01-27 US disclosed
US-7795270-B2 DUTPase inhibitors MEDIVIR AB (SE) 2010-09-14 US disclosed
US-20100075924-A1 DUTPASE INHIBITORS MEDIVIR AB (SE) 2010-03-25 US disclosed
US-7601702-B2 Dutpase Inhibitors MEDIVIR AB (SE) 2009-10-13 US disclosed
EP-1701727-A1 DUTPASE INHIBITORS Medivir Aktiebolag (SE) 2006-09-20 EP disclosed
WO-2005066160-A1 DUTPASE INHIBITORS MEDIVIR AB (SE) 2005-07-21 WO disclosed
WO-2005065689-A1 DUTPASE INHIBITORS MEDIVIR AB (SE) 2005-07-21 WO disclosed
EP-0642483-B1 CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF DOW CHEMICAL CO (US) 1998-02-18 EP disclosed
EP-0642483-A4 CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF. 1995-04-19 EP disclosed
EP-0642483-A1 CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF THE DOW CHEMICAL COMPANY (US) 1995-03-15 EP disclosed
US-5227560-A Vinylene or exomethylene groups from active methine compounds THE DOW CHEMICAL COMPANY (US) 1993-07-13 US disclosed
WO-1993009078-A1 CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF THE DOW CHEMICAL COMPANY (US) 1993-05-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110021459-A1 DUTPASE INHIBITORS DUT, DHODH, NAT10 MAOA 1544/4885MAOB 1062/4885ATM 4862/4885
US-20100075924-A1 DUTPASE INHIBITORS DUT, DHODH, CCNO MAOA 946/4885MAOB 463/4885ATM 4774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.