Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | FER | P16591 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589270 | 0.80 | LMNA (0.48) | ALDH1A1USP2LMNACYP1A2CHRM2 | |
| SCHEMBL1933106 | 0.70 | CYP1A2 (0.56) | CYP1A2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL1934670 | 0.69 | CHRM2 (0.63) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9202802 | 0.69 | ALOX15 (0.53) | RIPK1TSHR | |
| SCHEMBL10483573 | 0.65 | MEN1 (0.40) | KDM4EGLAMEN1KMT2AALDH1A1 | |
| SCHEMBL9574157 | 0.65 | CHRM2 (0.67) | ALDH1A1USP2LMNACYP1A2CHRM2 | |
| Nuvenzepine SCHEMBL1817515 | 0.65 | CHRM2 (0.56) | ALDH1A1USP2LMNACYP1A2CHRM2 | |
| SCHEMBL10515664 | 0.64 | POLB (0.38) | KDM4EGLAMEN1KMT2AALDH1A1 | |
| SCHEMBL26136498 | 0.63 | LRRK2 (0.37) | KDM4EGLAALDH1A1PDGFRAFER | |
| SCHEMBL10516167 | 0.62 | PARP1 (0.37) | KDM4EGLAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013777-A1 | METHOD OF USING M1-SELECTIVE ANTIMUSCARINIC PYRIDOBENZODIAZEPINONES IN AXIAL MYOPIA THERAPY | MERCK & CO., INC. (US) | 1993-07-22 | — | — | WO | disclosed |