SCHEMBL921469

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL920506	0.92	CYP3A4 (0.54)	MAPK14HTTLMNACYP3A4SMN1; SMN2
	SCHEMBL919925	0.90	HTR2C (0.49)	MAPK14CYP3A4GALR3NR2F2KLKB1
	SCHEMBL920375	0.90	MAPK14 (0.51)	MAPK14HPGDMAPK8ALDH1A1CA2
	SCHEMBL921475	0.89	CYP3A4 (0.52)	MAPK14HPGDHTTCYP3A4SMN1; SMN2
	SCHEMBL920140	0.89	EGLN1 (0.51)	HPGDLMNASMN1; SMN2ALDH1A1GAA
	SCHEMBL921316	0.89	MAPK14 (0.53)	MAPK14HPGDHTTCYP3A4MMP13
	SCHEMBL920472	0.89	LIPG (0.44)	MAPK14HPGDHTTLMNACYP3A4
	SCHEMBL921215	0.89	AKR1B1 (0.44)	MAPK14HPGDCYP3A4GALR3NR2F2
	SCHEMBL921095	0.89	LIPG (0.47)	MAPK14HPGDHTTCYP3A4MMP13
	SCHEMBL921057	0.89	L3MBTL1 (0.48)	MAPK14HPGDHTTLMNAGALR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.