Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447121 | 0.92 | MAPT (0.51) | MAPTL3MBTL1KDM4ETP53NPSR1 | |
| SCHEMBL9207834 | 0.86 | KCNH2 (0.44) | MAPTL3MBTL1KDM4ESLC6A2SLC6A4 | |
| SCHEMBL7859944 | 0.85 | HTR1A (0.41) | MAPTL3MBTL1KDM4ETP53POLB | |
| SCHEMBL9447022 | 0.81 | HTR1A (0.46) | MAPTL3MBTL1KDM4ETP53NPSR1 | |
| SCHEMBL9447113 | 0.80 | L3MBTL1 (0.45) | MAPTL3MBTL1KDM4ETP53POLB | |
| SCHEMBL9447066 | 0.73 | ADRA2B (0.38) | HTR1AMEN1GAAKMT2A | |
| SCHEMBL7861096 | 0.72 | KCNH2 (0.46) | DRD4DRD3 | |
| SCHEMBL10998289 | 0.71 | ALDH1A1 (0.60) | MAPTL3MBTL1KDM4ENPSR1SLC6A2 | |
| SCHEMBL7854338 | 0.69 | HTR1A (0.36) | MAPTL3MBTL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7861121 | 0.68 | HRH3 (0.39) | MAPTPOLBALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423802-B1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMA (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5134154-A | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0423802-A1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-24 | — | — | EP | disclosed |