Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203749 | 1.00 | MEN1 (0.41) | MEN1KMT2ACHRM3CHRM2CHRM1 | |
| SCHEMBL9200471 | 0.77 | KMT2A (0.49) | MEN1KMT2ACHRM3CHRM2CHRM1 | |
| SCHEMBL9200469 | 0.77 | KMT2A (0.49) | MEN1KMT2ACHRM3CHRM2CHRM1 | |
| SCHEMBL9198552 | 0.73 | ALDH1A1 (0.42) | MEN1KMT2ACHRM3CHRM2CHRM1 | |
| SCHEMBL9198555 | 0.73 | ALDH1A1 (0.42) | MEN1KMT2ACHRM3CHRM2CHRM1 | |
| SCHEMBL27406157 | 0.71 | ESR1 (0.43) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9200033 | 0.70 | NOS3 (0.55) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9196158 | 0.68 | CHRM1 (0.45) | CHRM3CHRM2CHRM1ALDH1A1CHRM5 | |
| SCHEMBL9196156 | 0.68 | CHRM1 (0.45) | CHRM3CHRM2CHRM1ALDH1A1CHRM5 | |
| SCHEMBL5929696 | 0.67 | LMNA (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382687-B1 | Benzofused-N-containing heterocycle derivatives | BOEHRINGER INGELHEIM ITALIA (IT) | 1995-12-27 | — | — | EP | disclosed |
| US-5106851-A | Respiratory system disorders | ISTITUTO DE ANGELI S.P.A. (IT) | 1992-04-21 | — | — | US | disclosed |
| EP-0382687-A2 | Benzofused-N-containing heterocycle derivatives | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1990-08-16 | — | — | EP | disclosed |