SCHEMBL9204069

SCHEMBL9204069

NC1=C(N)C(=O)c2cc3ccccc3cc2C1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
NPC1 O15118 4/20 0.46
RAB9A P51151 4/20 0.46
CYP3A4 P08684 3/20 0.46
TP53 P04637 3/20 0.46
NSD2 O96028 2/20 0.46
POLB P06746 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TSHR P16473 2/20 0.46
MAPK1 P28482 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 3/20 0.45
LMNA P02545 2/20 0.45
PTPRC P08575 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
NCOA1 Q15788 2/20 0.45
APAF1 O14727 1/20 0.45
TDP2 O95551 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1170208 0.89 ALDH1A1 (0.45) ALDH1A1NPC1RAB9ACYP3A4TP53
SCHEMBL8893581 0.85 ALDH1A1 (0.43) ALDH1A1NPC1RAB9ACYP3A4TP53
SCHEMBL30130196 0.84 MEN1 (0.56) ALDH1A1NPC1RAB9ACYP3A4TP53
SCHEMBL354514 0.84 MEN1 (0.56) ALDH1A1NPC1RAB9ACYP3A4TP53
SCHEMBL29364188 0.84 MEN1 (0.56) ALDH1A1NPC1RAB9ACYP3A4TP53
SCHEMBL29634145 0.81 MEN1 (0.53) ALDH1A1NPC1RAB9ACYP3A4TP53
SCHEMBL16144676 0.81 MEN1 (0.53) ALDH1A1NPC1RAB9ACYP3A4TP53
SCHEMBL19230417 0.81 ALDH1A1 (0.52) ALDH1A1NPC1RAB9ATP53NSD2
SCHEMBL30458681 0.81 MEN1 (0.53) ALDH1A1NPC1RAB9ACYP3A4TP53
Ammonia Solution, Strong SCHEMBL28255083 0.81 MEN1 (0.53) ALDH1A1NPC1RAB9ACYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108530365-B 1, 4-naphthoquinone/anthraquinone imidazole derivative and preparation and application thereof 上海交通大学 2020-07-14 CN claimed
EP-0279016-B2 Powdered hair dye HOYU KK (JP) 1995-04-05 EP claimed
US-20210036237-A1 ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE ORGANIC COMPOUND LG DISPLAY CO., LTD. (KR) 2021-02-04 US disclosed
CN-108530365-B 1, 4-naphthoquinone/anthraquinone imidazole derivative and preparation and application thereof 上海交通大学 2020-07-14 CN disclosed
EP-0047205-B1 PROCESS FOR THE PREPARATION OF ALPHA-BENZAMIDO-ALPHA'-HALOGEN-1,1'-DIANTHRIMIDES, ALPHA-BENZAMIDO-5' OR 8'-HALOGEN-1,1'-DIANTHRIMIDES AND THEIR APPLICATION AS INTERMEDIATES FOR VAT DYES I.C.I. FRANCOLOR S.A. (FR) 1984-04-25 EP disclosed
EP-0047205-A2 Process for the preparation of alpha-benzamido-alpha'-halogen-1,1'-dianthrimides, alpha-benzamido-5' or 8'-halogen-1,1'-dianthrimides and their application as intermediates for vat dyes I.C.I. FRANCOLOR S.A. (FR) 1982-03-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210036237-A1 ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE ORGANIC COMPOUND OCIAD1, OCIAD2, ORC3 ALDH1A1 412/4885NPC1 780/4885RAB9A 1895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.