Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 3/20 | 0.43 |
| ▸ | CASP7 | P55210 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HBB | P68871 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | PTPRC | P08575 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | S100A4 | P26447 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 2/20 | 0.42 |
| ▸ | TDP2 | O95551 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170208 | 0.96 | ALDH1A1 (0.45) | ALDH1A1HSD17B10CYP3A4CASP1CASP7 | |
| SCHEMBL9204069 | 0.85 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP3A4CASP1CASP7 | |
| SCHEMBL2516264 | 0.80 | MEN1 (0.50) | ALDH1A1HSD17B10CYP3A4CASP1CASP7 | |
| SCHEMBL54876 | 0.80 | MEN1 (0.50) | ALDH1A1HSD17B10CYP3A4CASP1CASP7 | |
| SCHEMBL10057987 | 0.80 | MEN1 (0.50) | ALDH1A1HSD17B10CYP3A4CASP1CASP7 | |
| SCHEMBL27981640 | 0.78 | APAF1 (0.41) | ALDH1A1HSD17B10CYP3A4CASP1CASP7 | |
| SCHEMBL19230417 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CASP1CASP7HIF1A | |
| SCHEMBL5145444 | 0.77 | PTPRC (0.59) | ALDH1A1HSD17B10CYP3A4CASP1CASP7 | |
| SCHEMBL652915 | 0.76 | MEN1 (0.60) | ALDH1A1HSD17B10CYP3A4CASP1CASP7 | |
| SCHEMBL354514 | 0.75 | MEN1 (0.56) | ALDH1A1HSD17B10CYP3A4CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594158-A | Processes for producing doxorubicin, daunomycinone, and derivatives of doxorubicin | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1997-01-14 | — | — | US | claimed |
| US-5594158-A | Processes for producing doxorubicin, daunomycinone, and derivatives of doxorubicin | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0523289-A1 | Processes for producing doxorubicin, daunomycinone, and derivatives of doxorubicin | Board of Regents of the University of Nebraska (US) | 1993-01-20 | — | — | EP | disclosed |